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Nitazoxanide 200 mg is generally recommended to be taken with food to enhance its absorption and reduce the risk of gastrointestinal side effects. However, in some cases, it can be taken on an empty stomach depending on the individual's tolerance and specific medical condition. The absorption of Nizonide 200 may be slightly reduced when taken without food, but it is still effective treating in certain parasitic and viral infections. It's essential to follow the prescribing physician's instructions regarding dosage and administration. If there are concerns about taking nitazoxanide on an empty stomach due to potential side effects or decreased absorption, consulting a healthcare professional is advised. They can provide personalized guidance based on the individual's health status and medical history, ensuring safe and effective use of the medication.